Glyphosate Causes Irreversible Abnormal Growth & Delayed Development of Embryonic Rat Neuronal Cells
- Details
- Published on Friday, 12 February 2016 12:59
The intended recipient for this message is julia.....
The Institute of Science in Society
Science Society Sustainability
www.i-sis.org.ukThis article can be found on the I-SIS website at http://www.i-sis.org.uk/Glyphosate_Causes_Abnormal_Neuronal_Development.php
If you would like to be removed from our mailing list unsubscribe at http://www.i-sis.org.uk/unsubscribe
or email
This email address is being protected from spambots. You need JavaScript enabled to view it.
ISIS Report 20/01/16
Glyphosate Causes Irreversible Abnormal Growth & Delayed Development of Embryonic Rat Neuronal Cells
Primary rat neuronal cultures exposed to glyphosate showed abnormal morphology, delayed differentiation and decreased activity of a Wnt signalling pathway involved in embryonic development Dr Eva Sirinathsinghji
Please circulate widely and repost, but you must give the URL of the original and preserve all the links back to articles on our website. If you find this report useful, please support ISIS by subscribing to our magazine Science in Society, and encourage your friends to do so. Or have a look at the ISIS bookstorefor other publications
A new study finds that cultured embryonic rat neurones exposed to sub-lethal doses of glyphosate show a delay in development characterised by reduced neuronal polarisation, complexity and morphology. Underlying the abnormalities was reduced activity of a Wnt protein Wnt5a, a signalling transduction molecule, as well as its downstream signalling effector CaMKII (Ca2+/calmodulin-dependent protein kinase II). Effects of glyphosate were rescued through the restoration of normal Wnt signalling activity, validating its involvement in glyphosate?s neurotoxic effects.
The toxicity of glyphosate herbicides and their formulation products are widely recognised in the scientific literature, with evidence accumulating on its neurotoxic effects (see [1] Banishing Glyphosate, Special ISIS report). Studies have linked glyphosate to Parkinson?s disease following acute exposure, increased seizures in epileptic patients, and deficits in learning and memory; and there is epidemiological evidence of increased behavioural problems in children such as ADHD (see [1]). Further, a recent investigation into neurotoxic mechanisms identified increased oxidative stress and cell death in the hippocampus of exposed rats linked to increased levels of extracellular glutamate neurotransmitter [2]. Nevertheless, cellular mechanisms underlying nervous system damage remained unknown.
Monsanto Face People’s Trial for Crimes against Humanity
- Details
- Published on Monday, 14 December 2015 06:14
The Organic Consumers Association (OCA), IFOAM International Organics, Navdanya, Regeneration International (RI), and Millions Against Monsanto, joined by dozens of global food, farming and environmental justice groups announced today that they will take Monsanto MON (NYSE), a US-based transnational corporation, to a people’s trial for crimes against nature and humanity, and ecocide, in The Hague, Netherlands, next year on World Food Day, October 16, 2016.
http://sustainablepulse.com/2015/12/03/monsanto-put-on-trial-for-crimes-against-humanity-in-the-hague/#.Vm5d7V51u2bPolish Farmers Released – On Bail
- Details
- Published on Thursday, 05 November 2015 06:33
The Farmers who blocked the sale of farmland in North West Poland have been released on bail. However, charges are still pending and the Polish government has washed its hands of the incident by claiming that the Prosecutor is independent and must arrive at his own conclusions. If convicted they face a potential five-TEN years imprisonment.
Polish GM ban now "agreed" to
- Details
- Published on Monday, 02 November 2015 06:29
Renewal Assessment Report - Glyphosate
- Details
- Published on Monday, 26 October 2015 18:21
How the War Against Nature Began
- Details
- Published on Monday, 26 October 2015 18:13
Julian Rose, Contributor Waking Times
There can be no more certain way to decimate life on Earth than through the act of setting in reverse the natural expansiveness of nature. Yet that is exactly what has been happening for the past two centuries, through the relentless through the relentless eradication of farm and forest biodiversity in a fixated, tunnel vision pursuit of specialisation and profit.
http://www.wakingtimes.com/2015/10/21/how-the-war-against-nature-began
