Glyphosate Causes Irreversible Abnormal Growth & Delayed Development of Embryonic Rat Neuronal Cells
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- Published on Friday, 12 February 2016 12:59
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ISIS Report 20/01/16
Glyphosate Causes Irreversible Abnormal Growth & Delayed Development of Embryonic Rat Neuronal Cells
Primary rat neuronal cultures exposed to glyphosate showed abnormal morphology, delayed differentiation and decreased activity of a Wnt signalling pathway involved in embryonic development Dr Eva Sirinathsinghji
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A new study finds that cultured embryonic rat neurones exposed to sub-lethal doses of glyphosate show a delay in development characterised by reduced neuronal polarisation, complexity and morphology. Underlying the abnormalities was reduced activity of a Wnt protein Wnt5a, a signalling transduction molecule, as well as its downstream signalling effector CaMKII (Ca2+/calmodulin-dependent protein kinase II). Effects of glyphosate were rescued through the restoration of normal Wnt signalling activity, validating its involvement in glyphosate?s neurotoxic effects.
The toxicity of glyphosate herbicides and their formulation products are widely recognised in the scientific literature, with evidence accumulating on its neurotoxic effects (see [1] Banishing Glyphosate, Special ISIS report). Studies have linked glyphosate to Parkinson?s disease following acute exposure, increased seizures in epileptic patients, and deficits in learning and memory; and there is epidemiological evidence of increased behavioural problems in children such as ADHD (see [1]). Further, a recent investigation into neurotoxic mechanisms identified increased oxidative stress and cell death in the hippocampus of exposed rats linked to increased levels of extracellular glutamate neurotransmitter [2]. Nevertheless, cellular mechanisms underlying nervous system damage remained unknown.
Monsanto Face People’s Trial for Crimes against Humanity
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- Published on Monday, 14 December 2015 06:14
The Organic Consumers Association (OCA), IFOAM International Organics, Navdanya, Regeneration International (RI), and Millions Against Monsanto, joined by dozens of global food, farming and environmental justice groups announced today that they will take Monsanto MON (NYSE), a US-based transnational corporation, to a people’s trial for crimes against nature and humanity, and ecocide, in The Hague, Netherlands, next year on World Food Day, October 16, 2016.
http://sustainablepulse.com/2015/12/03/monsanto-put-on-trial-for-crimes-against-humanity-in-the-hague/#.Vm5d7V51u2bPolish GM ban now "agreed" to
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- Published on Monday, 02 November 2015 06:29
Renewal Assessment Report - Glyphosate
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- Published on Monday, 26 October 2015 18:21
Two thirds of EU cropland, population ditch GM crops
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- Published on Wednesday, 07 October 2015 05:00
The Ecologist, 1st October 2015
Living with GMOs - a letter from America
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- Published on Saturday, 15 November 2014 12:49
NGOs, scientists, anti-GM groups, celebrities, food manufacturers, and others representing 57 million Americans today publish an Open Letter to the UK and the entire EU warning of the serious and manifold hazards of GMO crops - and promising their support in our fight against them. We are writing as concerned American citizens to share with you our experience of genetically modified (GM) crops and the resulting damage to our agricultural system and adulteration of our food supply.
In our country, GM crops account for about half of harvested cropland. Around 94% of the soy, 93% of corn (maize) and 96% of cotton grown is GM.
The UK and the rest of the EU have yet to adopt GM crops in the way that we have, but you are currently under tremendous pressure from governments, biotech lobbyists, and large corporations to adopt what we now regard as a failing agricultural technology....
